Detalhe da pesquisa
1.
Cyclic Nucleotide Phosphodiesterases in Alcohol Use Disorders: Involving Gut Microbiota.
Int J Neuropsychopharmacol
; 26(1): 70-79, 2023 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36087271
2.
Rolipram Ameliorates Memory Deficits and Depression-Like Behavior in APP/PS1/tau Triple Transgenic Mice: Involvement of Neuroinflammation and Apoptosis via cAMP Signaling.
Int J Neuropsychopharmacol
; 26(9): 585-598, 2023 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37490542
3.
Imbalance of multiple neurotransmitter pathways leading to depression-like behavior and cognitive dysfunction in the triple transgenic mouse model of Alzheimer disease.
Metab Brain Dis
; 38(7): 2465-2476, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37256468
4.
Ischemic stroke/transient ischemic attack in adults with primary immune thrombocytopenia: a meta-analysis.
Neurol Sci
; 42(5): 2013-2020, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33006722
5.
The Phosphodiesterase-4 Inhibitor Roflumilast, a Potential Treatment for the Comorbidity of Memory Loss and Depression in Alzheimer's Disease: A Preclinical Study in APP/PS1 Transgenic Mice.
Int J Neuropsychopharmacol
; 23(10): 700-711, 2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32645141
6.
Brucine N-Oxide Reduces Ethanol Intake and Preference in Alcohol-Preferring Male Fawn-Hooded Rats.
Alcohol Clin Exp Res
; 44(6): 1321-1328, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32343845
7.
Adjuvant therapy with Astragalus membranaceus for post-stroke fatigue: a systematic review.
Metab Brain Dis
; 35(1): 83-93, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31440984
8.
GABAergic System in Stress: Implications of GABAergic Neuron Subpopulations and the Gut-Vagus-Brain Pathway.
Neural Plast
; 2020: 8858415, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32802040
9.
Protection from Amyloid ß Peptide-Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor.
J Pharmacol Exp Ther
; 371(2): 250-259, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31488603
10.
The Rho kinase inhibitor fasudil attenuates Aß1-42-induced apoptosis via the ASK1/JNK signal pathway in primary cultures of hippocampal neurons.
Metab Brain Dis
; 34(6): 1787-1801, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31482248
11.
Therapeutic potentials of the Rho kinase inhibitor Fasudil in experimental autoimmune encephalomyelitis and the related mechanisms.
Metab Brain Dis
; 34(2): 377-384, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30552558
12.
Identification of a PDE4-Specific Pocket for the Design of Selective Inhibitors.
Biochemistry
; 57(30): 4518-4525, 2018 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29975048
13.
Adeno-associated virus 9-mediated Cdk5 inhibitory peptide reverses pathologic changes and behavioral deficits in the Alzheimer's disease mouse model.
FASEB J
; 31(8): 3383-3392, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28420695
14.
The phosphodiesterase-4 inhibitor rolipram attenuates heroin-seeking behavior induced by cues or heroin priming in rats.
Int J Neuropsychopharmacol
; 17(9): 1397-407, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24832929
15.
Antidepressant-like effects of the phosphodiesterase-4 inhibitor etazolate and phosphodiesterase-5 inhibitor sildenafil via cyclic AMP or cyclic GMP signaling in mice.
Metab Brain Dis
; 29(3): 673-82, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24705918
16.
Discovery of novel positive allosteric modulators targeting GluN1/2A NMDARs as anti-stroke therapeutic agents.
RSC Med Chem
; 15(4): 1307-1319, 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38665828
17.
cGAS/STING signaling pathway-mediated microglial activation in the PFC underlies chronic ethanol exposure-induced anxiety-like behaviors in mice.
Int Immunopharmacol
; 134: 112185, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38701540
18.
Chronic pain exacerbates memory impairment and pathology of Aß and tau by upregulating IL-1ß and p-65 signaling in a mouse model of Alzheimer's disease.
Brain Res
; 1832: 148843, 2024 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38430996
19.
The evaluation of AZ66, an optimized sigma receptor antagonist, against methamphetamine-induced dopaminergic neurotoxicity and memory impairment in mice.
Int J Neuropsychopharmacol
; 16(5): 1033-44, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22932447
20.
ß-Glucan attenuates cognitive impairment of APP/PS1 mice via regulating intestinal flora and its metabolites.
CNS Neurosci Ther
; 29(6): 1690-1704, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36890624